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霍小位

更新时间:2020-08-22 11:55:05点击次数:




霍小位,博士,硕士生导师,毕业于北京协和医学院。主要从事天然产物及小分子化合物的抗肿瘤活性及分子机制研究。

主持国家自然科学基金项目1项、河北省自然科学基金项目2项,河北省教育厅项目1项。发表SCI收录论文20余篇。主讲课程《药理学》、《人体解剖生理学》等。

联系方式:huoxiaoweiforever@163.com

研究方向

1. 天然产物及小分子化合物的抗肿瘤活性筛选、抗肿瘤分子靶标及作用机理研究

2. 抗炎及抗氧化药物活性筛选及分子机制研究

代表性论著

[1] MY Chen, Y Hou, N Chen, EL Yang, ZC Sun, HF Wu, XD Xu, JS Yang, GX Ma*, XW Huo*. Co-assemblies based on natural Hemslecin A and β-sitosterol as a new sight for synergistic anti-gastric cancer efficacy in TCM. Colloid and Interface Science Communications, 2022, 49.

[2] DL Chen#, ZC Sun#, YY Liu, ZY Li, HQ Liang, L Chen, XD Xu, JS Yang, GX Ma*, XW Huo*. Eleucanainones A and B: Two dimeric structures from the bulbs of Eleutherine americana with anti-MRSA activity. Organic Letters, 2020, 22(9).

[3] XW Huo#, CQ Liu#, L Gao, XD Xu, NL Zhu*, L Cao*. Hepatoprotective effect of aqueous extract from the seeds of Orychophragmus violaceus against liver injury in mice and HepG2 cells. International Journal of Molecular Sciences, 2017, 18(6): 1197.

[4] LL Zhang#, XW Huo#, YH Liao, FF Yang, L Gao, L Cao*. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Scientific Reports, 2017, 7(1).

[5] XW Huo, YM Jia, DY Liu, L Gao, LJ Zhang, LY Li, Y Qi*, L Cao*. Photodynamic diagnosis of gastric cancer using HPPH-CD. Rsc Advances, 2016, 6(45): 39216-39224.